condition in dichloromethane using both polyaniline supported TsOH (PANI-TsOH) and FeCl 3 (PANI- FeCl 3) as reusable acid catalysts with the formation of 2,4-disubstituted tetrahydropyran ether as single product. In case of 4-, 3- and 2- nitro benzaldehydes, the reaction generated acetal of the aldehyde and homoallylic alcohol as single product.
Diazomethane is the chemical compound CH 2 N 2, discovered by German chemist Hans von Pechmann in 1894. It is the simplest diazo compound.In the pure form at room temperature, it is an extremely sensitive explosive yellow gas; thus, it is almost universally used as a solution in diethyl ether.
Tsoh reaction with alcohol
The Michael reaction is the reaction of carbon nucleophiles in nucleophilic conjugate addition. In hetero-Michael additions the nucleophile is an amine, thiol, phosphine or in the specific case of a oxa-Michael addition an alcohol (Review DOI). A base is required and the reaction product is a beta-alkoxy carbonyl.
Environmental and cost concerns are spurring development of chemical methods that minimize byproduct formation. In this vein, Mo and Dong present a catalyst that inserts olefins such as ethylene directly into the C-H bonds of ketones. Traditional methods to form such products rely on the preliminary reaction of the ketone with a base, followed by subsequent reaction with an alkyl halide. The ...
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